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Common hepatitis C drugs available in Canada for adults

Treatments for all genotypes

Brand name (generic name)GenotypesImageDosage scheduleFood requirementsWeeks of treatment

Epclusa
(velpatasvir + sofosbuvir)

with or without ribavirin*

AllOne tablet once dailyNo food restrictions12
Maviret
(glecaprevir + pibrentasvir)
AllThree tablets once dailyTake with food8, 12 or 16

Treatment for specific genotypes

Brand name (generic name)GenotypesImageDosage scheduleFood requirementsWeeks of treatment
Harvoni
(ledipasvir + sofosbuvir)
1a, 1b, 4, 5, 6One tablet once dailyNo food restrictions8 or 12

Retreatment if Epclusa, Maviret or Harvoni failed to cure infection

Brand name (generic name)GenotypesImageDosage scheduleFood requirementsWeeks of treatment
Vosevi
(sofosbuvir + velpatasvir
+ voxilaprevir)
AllOne tablet once dailyTake with food12

*ribavirin as a possible treatment addition

Ibavyr
(ribavirin)


1,000 mg for under 75 kg and 1,200 mg for 75 kg or more, twice dailyTake with foodSee above 

 

NOTE

This chart is not a complete list of Health Canada-approved treatments for hepatitis C. This chart lists common daily dosing schedules. People should always follow the dosing schedule prescribed by their healthcare provider. Healthcare providers can check for drug interactions between hepatitis C treatment and other drugs a person is taking with a pharmacist or at www.hep-druginteractions.org.

Disclaimer

CATIE endeavours to provide up-to-date and accurate information at the time of publication, but it should not be considered medical advice. Decisions about particular medical treatments should always be made in consultation with a qualified medical practitioner. CATIE resources may contain descriptions or depictions of sex, sexuality or drug use, with the goal of promoting public health. Any opinions expressed herein may not reflect the policies or opinions of CATIE or any partners or funders.

Acknowledgements

Epclusa®, Harvoni® and Vosevi™ are trademarks of Gilead Sciences, Inc., or its related companies. Images of Epclusa, Harvoni and Vosevi, copyright Gilead Sciences, Inc., or its related companies. Used with permission. Maviret™ is a trademark of AbbVie Corporation. Image of Maviret is copyright AbbVie Corporation. Used with permission. Ibavyr™ is a trademark of Pharmascience Inc. Images used with permission.

Production of this publication has been made possible through a financial contribution from the Public Health Agency of Canada and the Ontario Ministry of Health. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada or other funders.