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TreatmentUpdate 176Volume 22 Issue 1 2010 January I ANTI-HIV AGENTS - E. Simplifying therapyThe panel provides several scenarios for doctors to consider when thinking about simplifying a patient’s regimen. The panel takes a broad view of simplification—this can mean anything from taking fewer doses to enhancing tolerability to reducing food and water requirements needed by some regimens. Simplifying therapy can help to improve the quality of life of some patients. Studies have found that simpler regimens are associated with better adherence. According to the panel, patients who are taking their first regimen and who do not have a history of treatment failure are ideal candidates for regimen simplification. In selected cases, the panel notes that even people with previous documented or suspected drug resistance may be appropriate candidates for simplification provided that their current regimens are fully suppressive. The panel provides detailed scenarios in which simplification may occur. It also offers tips for helping to make a smooth transition in order to ensure that the new regimen is working. One of the most important points made by the panel is that close monitoring for the first two to six weeks after simplifying a regimen is needed to ensure tolerability of the new regimen as well as to ensure viral and immunologic response to therapy. Created on: 2010 January 25 Author: Hosein SR |
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Decisions about particular medical treatments should always be made in consultation with a qualified medical practitioner who is knowledgeable about HIV-related illness and the treatments in question. MORE | |