Side effects | CATIE - Canada's source for HIV and hepatitis C information

Hepatitis C: An In-Depth Guide

Side effects

Many of the problems that were common with the hepatitis C treatments available early in the epidemic have been eliminated.

Always seek a full diagnosis from your healthcare provider regarding all symptoms. What you’re feeling could be from your medication, but it could also be a hormone problem, a nutrient deficiency, an infection, depression, hepatitis C infection itself or something else.

The most common side effects experienced by people taking direct-acting antivirals (DAAs) include headache, tiredness (fatigue), nausea and diarrhea. These side effects are usually mild or moderate and diminish or stop after a few weeks of treatment. People who take ribavirin in addition to DAAs may experience additional side effects such as irritability, difficulty sleeping, lowered red blood cell count (anemia) and a rash or itchy skin (pruritus).

Most side effects are mild and can be managed with support from your healthcare provider. In rare instances, severe side effects may require a change in treatments.

The following list includes common symptoms that may be side effects of hepatitis C treatment. Click on the symptom to find out more about the condition, including the cause of the symptom and tips on managing the symptom.

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