Hepatitis C: An In-Depth Guide

Blisters (poryphyria cutanea tarda)

Fluid-filled blisters on the hands or on any area of the body exposed to sunlight may be caused by a disorder called porphyria cutanea tarda. This condition may also cause darkening or lightening of the skin, hair loss and thickening of the skin.


Porphyria cutanea tarda is a symptom of hepatitis C. It is caused by an overproduction of the protein uroporphyrinogen where hepatitis C blocks the removal of waste products (porphyrins) from the blood.


  • Although not curable, symptoms can be managed. Ask your doctor about low dose chloroquine or hydroxylchloroquine (anti-malarial drugs).


Reduce your intake of foods that contain iron.

Reduce your consumption of alcohol.

Avoid the sun or use sun block.