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A Practical Guide to HAART (Highly Active Anti-retroviral Therapy)

Revised 2006

Table of Contents

A Practical Guide to HAART (Highly Active Anti-Retroviral Therapy)
	Important Note to the Reader
	Acknowledgments and credits
A Practical Guide to HAART, PART 1 - HIV and AIDS: The Basics
	Introduction
	The Viral Life Cycle
	The HIV Virus
	HIV enters a cell
	HIV takes control of the cell
	HIV becomes part of the infected cell
	HIV tricks the infected cell into making copies of itself
	The Immune System
	Outside the Body
	Inside the Body
	Immune Cells You Need to Know About
	HIV and Your Immune System
	The Stages of HIV Infection
	Primary Infection
	Asymptomatic Infection
	Symptomatic Infection
	AIDS
	Monitoring Your Immune System and the Virus
	CD4+ count
	CD4+ percentage
	CD8+ count
	Interpreting Immune Cell Changes
	Factors that Affect Immune Cell Counts and Ways to Reduce Variation
	Viral load
	Drug Resistance
A Practical Guide to HAART, PART 2 - Treating HIV and AIDS
	Before, During and After Starting Drug Treatment: The Body’s Basic Elements of Health
	Good Nutrition
	Hormone Replacement
	Exercise
	Program the Mind Toward Healing
	Starting Drug Treatment: When
	Working with Your Doctor
	Issues to Consider Before Starting Treatment
	Choosing Treatment: With What
	A protease inhibitor–based regimen
	A protease-sparing regimen
	A two-class-sparing all-nukes regimen
	The kitchen-sink regimen
	A kinder, simpler regimen: once-daily therapy
	Drug Interactions
	Continuing Treatment: Making it Work Long-Term
	Changing Treatment
	Stopping Treatment
	Boosting the Immune System
	To make drug-resistant virus sensitive to treatment
	To improve quality of life
	Cautions on Stopping Therapy
	What to expect if you take a break
	The End....But Not Really
Appendix A: Antiretroviral Drugs
	Preface
	Entry inhibitors and fusion inhibitors
	Reverse transcriptase inhibitors
	Nukes or NRTIs (approved in Canada)
	Nucleotide RTI (approved in Canada)
	Non-nukes or NNRTIs (approved in Canada)
	Integrase inhibitors
	Protease inhibitors
	Protease inhibitors (approved in Canada)

Decisions about particular medical treatments should always be made in consultation with a qualified medical practitioner who is knowledgeable about HIV-related illness and the treatments in question. MORE

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